Modeling tensional homeostasis in multicellular clusters
نویسندگان
چکیده
منابع مشابه
Tensional homeostasis in endothelial cells is a multicellular phenomenon.
Mammalian cells of various types exhibit the remarkable ability to adapt to externally applied mechanical stresses and strains. Because of this adaptation, cells can maintain their endogenous mechanical tension at a preferred (homeostatic) level, which is essential for normal physiological functions of cells and tissues and provides protection against various diseases, including atherosclerosis...
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To determine if tendon cell ciliary length could be used as a biomarker of cytoskeletal tensional homeostasis, 20 mm long adult rat tail tendons were placed in double artery clamps set 18 mm apart to create a 10% laxity. The tendons were allowed to contract over a 7 day period under culture conditions. At 0, 1, 5, and 7 days the tendon cell cilia were stained and ciliary length measured using c...
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ژورنال
عنوان ژورنال: International Journal for Numerical Methods in Biomedical Engineering
سال: 2016
ISSN: 2040-7939,2040-7947
DOI: 10.1002/cnm.2801